tert-butyl (benzyloxy)carbamate

tert-butyl (benzyloxy)carbamate - Names and Identifiers

Name	tert-butyl N-(benzyloxy)carbamate
Synonyms	LABOTEST-BB LT00452293 N-Boc-O-benzylhydroxylamine TERT-BUTYL BENZYLOXYCARBAMATE tert-butyl (benzyloxy)carbamate tert-butyl N-(benzyloxy)carbamate TERT-BUTYL N-(BENZYLOXY)CARBAMATE N-(BENZYLOXY)CARBAMIC ACID TERT-BUTYL ESTER N-(Benzyloxy)carbamic acid tert-butyl ester O-Benzylhydroxylamine, N-BOC protected, tert-Butyl (phenylmethoxy)carbamate
CAS	79722-21-7
EINECS	628-800-0
InChI	InChI=1/C12H17NO3/c1-12(2,3)16-11(14)13-15-9-10-7-5-4-6-8-10/h4-8H,9H2,1-3H3,(H,13,14)
InChIKey	MZNBNPWFHGWAGH-UHFFFAOYSA-N

tert-butyl (benzyloxy)carbamate - Physico-chemical Properties

Molecular Formula	C12H17NO3
Molar Mass	223.27
Density	1.078±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	45-47 °C (lit.)
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
Appearance	Solid
Color	White
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.505
MDL	MFCD00191873

tert-butyl (benzyloxy)carbamate - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29280000

tert-butyl (benzyloxy)carbamate - Introduction

tert-butyl N-(benzyloxy)carbamate is a chemical compound with the following properties:

1. Appearance: tert-butyl N-(benzyloxy)carbamate is a colorless to light yellow liquid or solid.

2. Solubility: It is soluble in most organic solvents, such as ethers, alcohols and ketones.

3. Melting point and boiling point: The melting point of tert-butyl N-(benzyloxy)carbamate is about 25-30°C, and the boiling point is about 100°C.

Use of tert-butyl N-(benzyloxy)carbamate:

1. as a protective group (protecting group): it can be used as an amino protecting agent for organic synthesis. By introducing a protecting group tert-butyl the N-(benzyloxy)carbamate, the amino compound can be prevented from participating in a predetermined reaction and the reactivity thereof can be protected.

2. Organic synthesis: tert-butyl N-(benzyloxy)carbamate can be used as reagents and intermediates in organic synthesis. It can be used in the synthesis of amides, ureas and other organic compounds.

Preparation of tert-butyl N-(benzyloxy)carbamate:

tert-butyl N-(benzyloxy)carbamate can be obtained by reacting benzyl alcohol with tert-butyl bicarbonate in the presence of a base.

Security information tert-butyl N-(benzyloxy)carbamate:

The safe operation of this compound should be carried out in a chemical laboratory and the corresponding laboratory safety regulations need to be observed. It may be irritating to the eyes, skin and respiratory tract, so adequate precautions should be taken during use.

Last Update：2024-04-09 20:49:11